Identification of novel β-lactams and pyrrolidinone derivatives as selective Histamine-3 receptor (H3R) modulators as possible anti-obesity agents

Anirban Ghoshal, Ajeet Kumar, D. Yugandhar, +8

European Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryBiochemistryNovel β-LactamsMedicine +8

Diagnosis of ectopic gastric mucosa using⁹⁹Tc^m-pertechnetate: spectrum of scintigraphic findings

Rakesh Kumar, Madhavi Tripathi, N. Chandrashekar, +4

British Journal of Radiology

Ectopic Gastric MucosaEsophagusGastric DuplicationAbdominal ImagingHistopathology +12

Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice

Chandan Sona, Ajeet Kumar, Shalini Dogra, +3

Neurobiology of Disease

Docosahexaenoic AcidMemory DeficitsAlzheimer's DiseaseBrain FunctionCognitive Neuroscience +8

Tango assay for ligand-induced GPCR–β-arrestin2 interaction

Shalini Dogra, Chandan Sona, Ajeet Kumar, +1

Methods in cell biology

Molecular PharmacologyBiochemistryG Protein-coupled ReceptorMedicineMechanism Of Action +4

Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression

Shalini Dogra, Ajeet Kumar, Deepmala Umrao, +2

Scientific Reports

Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis

Ajeet Kumar, Shalini Dogra, Chandan Sona, +5

Psychoneuroendocrinology

PsychoneuroimmunologyStress HormonePsychiatryMedicinePsychotropic Medication +10

Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration

Wolfgang Pita‐Thomas, Tássia Mangetti Gonçalves, Ajeet Kumar, +2

Scientific Reports

Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy

Lakhwinder Singh, Ajeet Kumar, Akanksha Upadhyay, +6

European Journal of Medicinal Chemistry

ObesityMetabolic SyndromeNiacin Receptor 1PharmacologyObesity Management +5

Identification of dual role of piperazine-linked phenyl cyclopropyl methanone as positive allosteric modulator of 5-HT2C and negative allosteric modulator of 5-HT2B receptors

Kartikey Singh, Chandan Sona, Vikas Ojha, +6

European Journal of Medicinal Chemistry

Drug TargetBiochemistryFunctional SelectivityDual RoleMedicine +8

Novel Tetrahydroquinazolinamines as Selective Histamine 3 Receptor Antagonists for the Treatment of Obesity

Ajeet Kumar, Venkata Reddy Pasam, Ravi Thakur, +17

Journal of Medicinal Chemistry