Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

William W. Busse, Eugene R. Bleecker, J Mark FitzGerald, +439

The Lancet Respiratory Medicine

AsthmaRheumatologyExtension TrialAllergyAllergy Medicine +8

Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids

Yoshihiro Kanemitsu, Hisako Matsumoto, Kenji Izuhara, +27

Journal of Allergy and Clinical Immunology

AsthmaPulmonary CirculationAllergyPhysiologyPeriostin Associates +7

Effects of a PAF antagonist, Y-24180, on bronchial hyperresponsiveness in patients with asthma.

Soichiro Hozawa, Yoshinori Haruta, Shinichi Ishioka, +1

American Journal of Respiratory and Critical Care Medicine

AsthmaMolecular PharmacologyMethacholine Challenge TestAllergyLung Inflammation +11

Using Exhaled Nitric Oxide and Serum Periostin as a Composite Marker to Identify Severe/Steroid-Insensitive Asthma

Tadao Nagasaki, Hisako Matsumoto, Yoshihiro Kanemitsu, +18

American Journal of Respiratory and Critical Care Medicine

AsthmaInflammatory Lung DiseaseAllergyComposite MarkerSerum Periostin +5

<i><scp>GLCCI</scp>1</i> variant accelerates pulmonary function decline in patients with asthma receiving inhaled corticosteroids

Yumi Izuhara, Hisako Matsumoto, Yoshihiro Kanemitsu, +27

Allergy

AsthmaAcute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunology +18

Asthma control and quality of life in a real-life setting: a cross-sectional study of adult asthma patients in Japan (ACQUIRE-2)

Mitsuru Adachi, Soichiro Hozawa, Masanori Nishikawa, +3

Journal of Asthma

Comparison of budesonide/formoterol Turbuhaler with fluticasone/salmeterol Diskus for treatment effects on small airway impairment and airway inflammation in patients with asthma

Soichiro Hozawa, Michikazu Terada, Maki Hozawa

Pulmonary Pharmacology & Therapeutics

AsthmaAllergyLung InflammationRespiratory DiseasesBudesonide/formoterol Turbuhaler +6

Increased expression of tumor necrosis factor-alpha, interleukin-6, platelet-derived growth factor-B and granulocyte-macrophage colony-stimulating factor mRNA in cells of bronchoalveolar lavage fluids from patients with sarcoidosis.

Shinichi Ishioka, Tadahito Saito, Keiko Hiyama, +5

PubMed

Inflammatory Lung DiseaseSarcoidosis PatientsLung InflammationImmunologyPathology +19

Somatic Mutation in Peripheral Lymphocytes of Former Workers at the Okunojima Poison Gas Factory

Jitsuro Yanagida, Soichiro Hozawa, Shinichi Ishioka, +7

Japanese Journal of Cancer Research

Poison Gas WorkersMustard GasSomatic MutationSomatic VariantAllergy +10

Comparison of the effects of budesonide/formoterol maintenance and reliever therapy with fluticasone/salmeterol fixed-dose treatment on airway inflammation and small airway impairment in patients who need to step-up from inhaled corticosteroid monotherapy

Soichiro Hozawa, Michikazu Terada, Maki Hozawa

Pulmonary Pharmacology & Therapeutics

Pulmonary CareAllergyLung InflammationPulmonary PharmacologyBudesonide/formoterol Maintenance +6