Thomas Wirth

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

Louis M. Staudt, Harinder Singh, Ranjan Sen et al. · Nature · 1986 · 710 citations

Immunogenetics, Octamer Motif, Autoimmune Disease +9

Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription

Theresa Marafioti, Michael Hummel, Hans‐Dieter Foss et al. · Blood · 2000 · 495 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

Thomas Wirth, Louis M. Staudt, David Baltimore · Nature · 1987 · 400 citations

Chromatin, Transcriptional Regulation, Lymphoid-specific Promoter Activity +12

Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation

Thomas Wirth, Hai‐Hui Xue, Deepa Rai et al. · Immunity · 2010 · 261 citations · Full text

Systems Biology, Autoimmune Disease, Core Signature +10

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

Stefan Zwilling, Harald König, Thomas Wirth · The EMBO Journal · 1995 · 226 citations · Full text

Chromatin, Transcriptional Regulation, Pou Domains +11