Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

John T. Crowl, Maximilian Heeg, Amir Ferry, +6

Nature Immunology

Functional AdaptationsT-regulatory CellImmunologyAutoimmunityCell Biology +5

The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion

Anna-Maria Globig, Steven Zhao, Jessica Roginsky, +15

Nature

Autonomic SystemMolecular PhysiologySympathetic Nervous SystemPhysiologyImmunology +7

Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry

Maria Elena Maccari, Hassan Abolhassani, Asghar Aghamohammadi, +61

Frontiers in Immunology

Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

Julian Thalhammer, Gerhard Kindle, Alexandra Nieters, +305

Journal of Allergy and Clinical Immunology

VaccinationPrimary ImmunodeficiencyMaternal ImmunizationInborn ErrorsAutoimmune Disease +10

Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2

Christian Klemann, Nadezhda Camacho-Ordóñez, Linlin Yang, +20

Frontiers in Immunology

Early-onset autoimmunity associated with SOCS1 haploinsufficiency

Jérôme Hadjadj, Carla N. Castro, Maud Tusseau, +40

Nature Communications

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

Jennifer W. Leiding, Tiphanie P. Vogel, Valentine G.J. Santarlas, +97

Journal of Allergy and Clinical Immunology

Stat3 Gain-of-function SyndromeMonogenic Early-onset LymphoproliferationAutoimmune DiseaseAutoantibody ProductionImmune Cell Development +11

Metabolic programs of T cell tissue residency empower tumour immunity

Miguel Reina‐Campos, Maximilian Heeg, Kelly T. Kennewick, +17

Nature

Cell TherapyCancer ImmunosurveillanceT-regulatory CellImmunologyTumor Immunity +8

Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T‐cell activation, differentiation and repertoire

Sandra Ammann, Kai Lehmberg, Udo zur Stadt, +7

European Journal of Immunology

The German National Registry of Primary Immunodeficiencies (2012–2017)

Sabine M. El-Helou, Anika-Kerstin Biegner, Sebastian Bode, +142

Frontiers in Immunology

Disease ProgressionGerman Pid-net RegistryImmunodeficienciesGenetic EpidemiologyDiagnosis +19