Engineering of human brain organoids with a functional vascular-like system

Bilal Çakir, Yangfei Xiang, Yoshiaki Tanaka, +19

Nature Methods

Tissue EngineeringEngineeringEpendymaBiofabricationCerebral Organoid +10

hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids

Yangfei Xiang, Yoshiaki Tanaka, Benjamin Patterson, +9

Cell stem cell

Cortical OrganoidsDevelopmental BiologyNeuroanatomyMedicineMorphogenesis +5

Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

Kun‐Yong Kim, Eriona Hysolli, In‐Hyun Park

Proceedings of the National Academy of Sciences

Modeling Supravalvular Aortic Stenosis Syndrome With Human Induced Pluripotent Stem Cells

Xin Ge, Yongming Ren, Óscar Bártulos, +15

Circulation

Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

Yangfei Xiang, Yoshiaki Tanaka, Benjamin Patterson, +13

Molecular Cell

Molecular NeuroscienceMolecular PhysiologyDevelopmental BiologyBrd4 FunctionFunctional Abnormalities +11

Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons

Yangfei Xiang, Kun‐Yong Kim, Joel Gelernter, +2

PLoS ONE

Molecular NeuroscienceDevelopmental BiologyAlcohol DependenceStem Cell ResearchAlcohol Metabolism +13

Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells

Lin Han, Hua‐Jun Wu, Haiying Zhu, +14

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationMethylation ProfileMolecular Biology +19

The RNA exosome nuclease complex regulates human embryonic stem cell differentiation

Cédric Belair, Soyeong Sim, Kun‐Yong Kim, +2

The Journal of Cell Biology

EngineeringGeneticsDifferentiation-related RnasStem Cell BiologyEpigenetics +18

MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons

Jennifer Larimore, Pearl V. Ryder, Kun‐Yong Kim, +9

PLoS ONE

Cellular NeurobiologySocial SciencesAutism Spectrum DisorderPsychiatric GeneticsStem Cells +22

X Chromosome of Female Cells Shows Dynamic Changes in Status during Human Somatic Cell Reprogramming

Kun‐Yong Kim, Eriona Hysolli, Yoshiaki Tanaka, +5

Stem Cell Reports

ChromatinInduced Pluripotent Stem CellDevelopmental BiologySomatic Cell GeneticsX Chromosome +13