p38 Mitogen-activated Protein Kinase and Extracellular Signal-regulated Kinases Play Distinct Roles in the Activation of Dendritic Cells by Two Representative Haptens, NiCl2 and 2,4-dinitrochlorobenzene

Setsuya Aiba, Hideaki Manome, Satoshi Nakagawa, +5

Journal of Investigative Dermatology

Signal TransductionSignaling PathwayMolecular PathwayCell RegulationReceptor Tyrosine Kinase +7

Abnormal NF-κB Function Characterizes Human Type 1 Diabetes Dendritic Cells and Monocytes

Zia U.A. Mollah, Saparna Pai, Craig Moore, +7

The Journal of Immunology

p38 Mitogen-Activated Protein Kinase Mediates Dual Role of Ultraviolet B Radiation in Induction of Maturation and Apoptosis of Monocyte-Derived Dendritic Cells

Satoshi Nakagawa, Tomoyuki Ohtani, Masato Mizuashi, +4

Journal of Investigative Dermatology

Signal TransductionReceptor Tyrosine KinasePhotocarcinogenesisApoptosisImmunology +8

Autoreactive Cytotoxic T Lymphocytes Acquire Higher Expression of Cytotoxic Effector Markers in the Islets of NOD Mice after Priming in Pancreatic Lymph Nodes

Kate L. Graham, Balasubramanian Krishnamurthy, Stacey Fynch, +5

American Journal Of Pathology

Islet TransplantationAutoimmune DiseaseLymphocyte DevelopmentT-regulatory CellImmune Regulation +8

H1 and H2 Histamine Receptors Are Absent on Langerhans Cells and Present on Dermal Dendritic Cells

Tomoyuki Ohtani, Setsuya Aiba, Masato Mizuashi, +3

Journal of Investigative Dermatology

InflammationSignal TransductionAllergyImmunologyAutoimmunity +6

Macrophage Colony-stimulating Factor in Cooperation with Transforming Growth Factor-β1 Induces the Differentiation of CD34+ Hematopoietic Progenitor Cells Into Langerhans Cells Under Serum-free Conditions Without Granulocyte-macrophage Colony-stimulating Factor

Zia U.A. Mollah, Setsuya Aiba, Satoshi Nakagawa, +6

Journal of Investigative Dermatology

CytokineLymphocyte DevelopmentImmune Cell DevelopmentGranulocyteImmunology +11

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon–Dependent Pathway

Zia U.A. Mollah, Hong Sheng Quah, Kate L. Graham, +18

Diabetes

Cord Blood CD34+ Cells Differentiate into Dermal Dendritic Cells in Co-Culture with Cutaneous Fibroblasts or Stromal Cells

Zia U.A. Mollah, Setsuya Aiba, Hideaki Manome, +2

Journal of Investigative Dermatology

Regenerative MedicineCutaneous FibroblastsStromal CellsSkin DevelopmentMedicine +9

Interleukin-3 in Cooperation with Transforming Growth Factor β Induces Granulocyte Macrophage Colony Stimulating Factor Independent Differentiation of Human CD34+ Hematopoietic Progenitor Cells into Dendritic Cells with Features of Langerhans Cells

Zia U.A. Mollah, Setsuya Aiba, Satoshi Nakagawa, +4

Journal of Investigative Dermatology

InflammationCytokineGranulocyteImmune Cell DevelopmentImmunology +9

Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice

Zia U.A. Mollah, Kate L. Graham, Balasubramanian Krishnamurthy, +5

PLoS ONE