Binkai Chi

Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA

Binkai Chi, Qingliang Wang, Guifen Wu et al. · Nucleic Acids Research · 2012 · 146 citations · Full text

Rna Splicing, Molecular Biology, Molecular Genetics +18

Exosome cofactor <scp>hMTR</scp> 4 competes with export adaptor <scp>ALYREF</scp> to ensure balanced nuclear <scp>RNA</scp> pools for degradation and export

Jing Fan, Bin Kuai, Guifen Wu et al. · The EMBO Journal · 2017 · 107 citations · Full text

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

Yong Yu, Binkai Chi, Wei Xia et al. · Nucleic Acids Research · 2015 · 80 citations · Full text

Neurogenomics, Als Patient Fibroblasts, Motor Neuron Disease +17

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki et al. · Scientific Reports · 2018 · 67 citations · Full text

A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18

Binkai Chi, K. Wang, Yifei Du et al. · Nucleic Acids Research · 2014 · 57 citations · Full text

Viral Replication, Engineering, Immunology +17