The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

V. Crippa, D. Sau, P. Rusmini, +10

Human Molecular Genetics

Hspb8 ExpressionCell DeathMolecular BiologyProteasome ActivityProtein Folding +14

TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells

Claudia Colombrita, Elisa Onesto, Francesca Megiorni, +5

Journal of Biological Chemistry

Mutation of SOD1 in ALS: a gain of a loss of function

D. Sau, Silvia De Biasi, L. Vitellaro‐Zuccarello, +11

Human Molecular Genetics

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisGenetic DisorderMedicineGenetics +12

Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts

Elisa Onesto, Claudia Colombrita, Valentina Gumina, +9

Acta Neuropathologica Communications

Aggregation and proteasome: The case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy

P. Rusmini, D. Sau, V. Crippa, +5

Neurobiology of Aging

Elongated Polyglutamine AggregationKinesiologySpinal Cord InjurySkeletal MusclePhysiology +7

Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis

Elisa Onesto, P. Rusmini, V. Crippa, +4

Journal of Neurochemistry

17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy

P. Rusmini, F. Simonini, V. Crippa, +6

Neurobiology of Disease

Endocrine MechanismMutant Androgen ReceptorHormonal ReceptorPhysiologyAutophagy +5

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models

Claudia Colombrita, Elisa Onesto, Emanuele Buratti, +5

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Transcriptional RegulationProtein FunctionSignal TransductionProtein ExpressionNatural Sciences +8

The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis

M. Galbiati, Elisa Onesto, A. Zito, +6

Pharmacological Research

Neuritin (cpg15) enhances the differentiating effect of NGF on neuronal PC12 cells

Graziella Cappelletti, M. Galbiati, Cristina L. Ronchi, +3

Journal of Neuroscience Research