Diffusion and Sedimentation Interaction Parameters for Measuring the Second Virial Coefficient and Their Utility as Predictors of Protein Aggregation

Atul Saluja, R. Matthew Fesinmeyer, Sabine Hogan, +2

Biophysical Journal

Biophysical ModelingEngineeringProtein AggregationSecond Virial CoefficientSedimentation Interaction Parameters +7

Effective charge measurements reveal selective and preferential accumulation of anions, but not cations, at the protein surface in dilute salt solutions

Yatin R. Gokarn, R. Matthew Fesinmeyer, Atul Saluja, +4

Protein Science

EngineeringMolecular BiologyAnalytical UltracentrifugationProtein SurfaceDilute Salt Solutions +19

Effect of Ions on Agitation- and Temperature-Induced Aggregation Reactions of Antibodies

R. Matthew Fesinmeyer, Sabine Hogan, Atul Saluja, +5

Pharmaceutical Research

Immunocytochemical TechniqueBioanalysisImmunologyImmunochemistryAntibody Engineering +7

Ultrasonic Storage Modulus as a Novel Parameter for Analyzing Protein-Protein Interactions in High Protein Concentration Solutions: Correlation with Static and Dynamic Light Scattering Measurements

Atul Saluja, Advait Badkar, David L. Zeng, +2

Biophysical Journal

Novel ParameterBiochemistryUltrasonic Storage ModulusProtein FoldingDynamic Light +7

Coarse-Grained Antibody Models for “Weak” Protein–Protein Interactions from Low to High Concentrations

Cesar Calero‐Rubio, Atul Saluja, Christopher J. Roberts

The Journal of Physical Chemistry B

Measurement of fluid viscosity at microliter volumes using quartz impedance analysis

Atul Saluja, Devendra S. Kalonia

AAPS PharmSciTech

Rheological MeasurementEngineeringMicrofabricationQuartz Impedance AnalysisFluid Mechanics +8

Relating Protein–Protein Interactions and Aggregation Rates From Low to High Concentrations

Ranendu Ghosh, Cesar Calero‐Rubio, Atul Saluja, +1

Journal of Pharmaceutical Sciences

High ConcentrationsProtein–protein InteractionsProtein ChemistryBiochemistryProtein Folding +8

Ultrasonic rheology of a monoclonal antibody (IgG2) solution: Implications for physical stability of proteins in high concentration formulations

Atul Saluja, Advait Badkar, David L. Zeng, +1

Journal of Pharmaceutical Sciences

EngineeringProtein FoldingRheological PropertyRheologyRheology Control +9

Application of high‐frequency rheology measurements for analyzing protein–protein interactions in high protein concentration solutions using a model monoclonal antibody (IgG2)

Atul Saluja, Advait Badkar, David L. Zeng, +2

Journal of Pharmaceutical Sciences

Protein ChemistryProtein–protein InteractionsBiochemistryNatural SciencesBioanalysis +6

Predicting Protein-Protein Interactions of Concentrated Antibody Solutions Using Dilute Solution Data and Coarse-Grained Molecular Models

Cesar Calero‐Rubio, Ranendu Ghosh, Atul Saluja, +1

Journal of Pharmaceutical Sciences

Protein-protein InteractionsProtein FoldingMedicineNatural SciencesAntibody Screening +10