Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study

Maxime J.M. van der Valk, Denise E. Hilling, Esther Bastiaannet, +65

The Lancet

International WatchSurgical OncologyGastrointestinal OncologyMedicineClinical Trials +7

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Robin Kate Kelley, Makoto Ueno, Changhoon Yoo, +208

The Lancet

UrologySurgical OncologyGastrointestinal OncologyMedicineBiliary Cancer +3

Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study

Laura M. Fernández, Guilherme Pagin São Julião, Nuno Figueiredo, +94

The Lancet Oncology

International WatchSurgical OncologyConditional Recurrence-free SurvivalMedicineCancer Recurrence +9

A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy

Carine El Sissy, Amos Kirilovsky, Marc Van den Eynde, +29

Clinical Cancer Research

Non-surgical management of rectal cancer. Series of 68 cases, long follow up in two leading centres in Argentina

Fernando Sánchez Loria, Soledad Iseas, Juan Manuel O’Connor, +8

Digestive and Liver Disease

Surgical OncologyColorectal SurgeryCancer RecurrenceNon-surgical ManagementLeading Centres +5

Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD)

Sofieke Temmink, Koen Peeters, Renu R. Bahadoer, +72

British journal of surgery

International Validation of the Immunoscore Biopsy in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy

Carine El Sissy, Amos Kirilovsky, C. Pagès, +40

Journal of Clinical Oncology

Watch and wait after a clinical complete response in rectal cancer patients younger than 50 years

Renu R. Bahadoer, Koen Peeters, Geerard L. Beets, +140

British journal of surgery

Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome

Mariano Golubicki, Laia Bonjoch, José G. Acuña-Ochoa, +18

JCI Insight

Genome InstabilitySomatic VariantGenetic DisorderMedicineGenetics +11

Lynch‐like syndrome is as frequent as Lynch syndrome in early‐onset nonfamilial nonpolyposis colorectal cancer

Marina Antelo, Mariano Golubicki, Enrique Roca, +11

International Journal of Cancer