SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

Mehdi Moustaqil, Emma Ollivier, Hsin-Ping Chiu, +10

Emerging Microbes & Infections

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease

Gabriela Mercado, Valentina Castillo, Paulina Soto, +5

Neurobiology of Disease

Neurodegenerative DiseasesSignal TransductionAutophagyNeurochemical BiomarkersNeuroprotection +7

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Maritza Oñate, Alejandra Catenaccio, Natalia Salvadores, +8

Cell Death and Differentiation

Parkinson DiseaseNecroptosis MachineryAutophagyCell DeathDegenerative Disease +11

Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein

André Leitão, Paulina Soto, Alexandre Chappard, +5

Communications Biology

Protein AssemblyMolecular BiologyNeurochemical BiomarkersAnalytical UltracentrifugationSynaptic Signaling +19

Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor

Mehdi Moustaqil, Frank Fontaine, Jeroen Overman, +9

Nucleic Acids Research

Sox DimerTranscriptional RegulationAngiogenesisSignaling PathwaySox18 Dimer +15

Posttransplant Lymphoproliferative Disorder in Pediatric Liver Transplantation

M. Uribe, Boyd Hunter, A. Alba, +4

Transplantation Proceedings

Transplant RejectionTransplantationHepatologySolid Organ TransplantationPediatric Liver Transplantation +3

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

Alex McCann, Jieqiong Lou, Mehdi Moustaqil, +13

Nucleic Acids Research

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Maritza Oñate, Alejandra Catenaccio, Natalia Salvadores, +8

SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts

Mehdi Moustaqil, Emma Ollivier, Hsin-Ping Chiu, +10

Innate Immune SystemViral PathogenesisImmunologyMolecular BiologyInnate Immunity +20

Chilean Experience in Liver Transplantation for Acute Liver Failure in Children

M. Uribe, A. Alba, Boyd Hunter, +10

Transplantation Proceedings

TransplantationHepatologySolid Organ TransplantationPediatricsAcute Liver Failure +4