Patrick Klopchin

On the formation of longmers in phosphorothioate oligodeoxyribonucleotide synthesis

Achim H. Krotz, Patrick Klopchin, Kathleen L. Walker et al. · Tetrahedron Letters · 1997 · 61 citations

Biosynthesis, Natural Sciences, Oligonucleotide +2

Selectivity of anion exchange chromatography and capillary gel electrophoresis for the analysis of phosphorothioate oligonucleotides

G. Susan Srivatsa, Patrick Klopchin, Micheal A Batt et al. · Journal of Pharmaceutical and Biomedical Analysis · 1997 · 53 citations

Phosphorothioate Oligonucleotides, Engineering, Biochemistry +14

Phosphorothioate oligonucleotides: Largely reduced (N-1)-mer and phosphodiester content through the use of dimeric phosphoramidite synthons

Achim H. Krotz, Patrick Klopchin, Douglas L. Cole et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 35 citations

Phosphorothioate Oligonucleotides, Dimeric Phosphoramidite Synthons, Bioorganic Chemistry +6

Improved Impurity Profile of Phosphorothioate Oligonucleotides Through the Use of Dimeric Phosphoramidite Synthons

Achim H. Krotz, Patrick Klopchin, Douglas L. Cole et al. · Nucleosides and Nucleotides · 1997 · 11 citations

Bioorganic Chemistry, Engineering, Molecular Biology +18