Melanie M. Brinkmann

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

You‐Me Kim, Melanie M. Brinkmann, Marie-Ève Paquet et al. · Nature · 2008 · 672 citations

Toll-like Receptors, Molecular Immunology, Innate Immune System +6

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

Boyoun Park, Melanie M. Brinkmann, Eric Spooner et al. · Nature Immunology · 2008 · 461 citations · Full text

Toll-like Receptors, Toll-like Receptor 9, Proteolytic Cleavage +11

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

Melanie M. Brinkmann, Eric Spooner, Kasper Hoebe et al. · The Journal of Cell Biology · 2007 · 425 citations · Full text

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

Jill Hénault, Jennifer Martinez, Jeffrey M. Riggs et al. · Immunity · 2012 · 330 citations

Autoimmune Disease, Autoantibody Production, Pathogenesis +10

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

Boyoun Park, Ludovico Buti, Sungwook Lee et al. · Immunity · 2011 · 172 citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +12