Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

Yoshiyuki Minegishi, Masako Saitō, Tomohiro Morio, +33

Immunity

InflammationCytokineSignal TransductionAutoimmune DiseaseImmune Cell Development +11

Tandem duplication of the <i>FLT3</i> gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children

Feng Xu, Tomohiko Taki, Hong Yang, +7

British Journal of Haematology

Mixed-phenotype Acute LeukemiaGeneticsPathologyMolecular GeneticsInternal Tandem Duplication +14

Cytogenetic findings and clinical features in acute leukemia and transient myeloproliferative disorder in Down's syndrome

Y Hayashi, Mitsuoki Eguchi, K Sugita, +7

Blood

Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia

Shu-Xia Guo, Tomohiko Taki, H. Ohnìshì, +6

Leukemia Research

Hematological MalignancyChromatinP15 GenesMedicineNatural Sciences +8

Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.

Xiao–Tang Kong, Kohmei Ida, Hitoshi Ichikawa, +16

PubMed

Improved outcome in the treatment of pediatric multifocal Langerhans cell histiocytosis

Akira Morimoto, Satoshi Ikushima, Naoko Kinukawa, +8

Cancer

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

M Kawamura, H. Ohnìshì, Shu-Xia Guo, +10

Leukemia Research

Hematological MalignancyCancer ResearchMixed-phenotype Acute LeukemiaMalignant Blood DisorderImmunology +6

Prospective multicenter trial comparing repeated immunosuppressive therapy with stem-cell transplantation from an alternative donor as second-line treatment for children with severe and very severe aplastic anemia

Yoshiyuki Kosaka, Hiroshi Yagasaki, Kimihiko Sano, +14

Blood

Frequency and clinical significance of the MLL gene rearrangements in infant acute leukemia.

Tomohiko Taki, K. Ida, Fumio Bessho, +8

PubMed

Six Months of Maintenance Chemotherapy After Intensified Treatment for Acute Lymphoblastic Leukemia of Childhood

Yasunori Toyoda, Atsushi Manabe, Masahiro Tsuchida, +18

Journal of Clinical Oncology