Leroy Hubert

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia

Francis P. Pankowicz, Mercedes Barzi, Xavier Legras et al. · Nature Communications · 2016 · 129 citations · Full text

Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline

Vincent Dion, Yunfu Lin, Leroy Hubert et al. · Human Molecular Genetics · 2008 · 97 citations · Full text

Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1

Leroy Hubert, Yunfu Lin, Vincent Dion et al. · Human Molecular Genetics · 2011 · 69 citations · Full text

A metabolomic map of Zellweger spectrum disorders reveals novel disease biomarkers

Michael F. Wangler, Leroy Hubert, Taraka Donti et al. · Genetics in Medicine · 2018 · 59 citations · Full text

Bioinformatics, Medicine, Genetics +13

Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum

Taraka Donti, Gerarda Cappuccio, Leroy Hubert et al. · Molecular Genetics and Metabolism Reports · 2016 · 53 citations · Full text

Genetics, Metabolomic Profiling, Pathology +17