CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations

Grégoire Cullot, Julian Boutin, Jérôme Toutain, +17

Nature Communications

High Clinical Value of Liquid Biopsy to Detect Circulating Tumor Cells and Tumor Exosomes in Pancreatic Ductal Adenocarcinoma Patients Eligible for Up-Front Surgery

Étienne Buscail, Catherine Alix‐Panabières, Pascaline Quincy, +14

Cancers

Characterization of acute kidney injury in critically ill patients with severe coronavirus disease 2019

Sébastien Rubin, Arthur Orieux, Renaud Prével, +22

Clinical Kidney Journal

BMP4 Regulates Pancreatic Progenitor Cell Expansion through Id2

Hong Hua, You-Qing Zhang, Sandrine Dabernat, +4

Journal of Biological Chemistry

Cell LineageLineage PlasticitySignal TransductionDevelopmental BiologyBmp4 Stimulation +9

CD63-GPC1-Positive Exosomes Coupled with CA19-9 Offer Good Diagnostic Potential for Resectable Pancreatic Ductal Adenocarcinoma

Étienne Buscail, Alexandre Chauvet, Pascaline Quincy, +13

Translational Oncology

Surgical OncologyPathologyExtracellular MicrovesiclesGpc1-positive ExosomesTumor Biology +15

CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells

Julian Boutin, Juliette Rosier, David Cappellen, +16

Nature Communications

Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders

Aurélie Bedel, François Béliveau, Isabelle Lamrissi‐Garcia, +8

Stem Cells Translational Medicine

Resveratrol and capsaicin used together as food complements reduce tumor growth and rescue full efficiency of low dose gemcitabine in a pancreatic cancer model

V. Vendrely, Evelyne Peuchant, Étienne Buscail, +7

Cancer Letters

Catalytic Mechanism of Nucleoside Diphosphate Kinase Investigated Using Nucleotide Analogues, Viscosity Effects, and X-ray Crystallography^,

Philippe Gonin, Yingwu Xu, Laurence Milon, +6

Biochemistry

Inhibition of Activin Signaling Induces Pancreatic Epithelial Cell Expansion and Diminishes Terminal Differentiation of Pancreatic β-Cells

You-Qing Zhang, Mary Malo Cleary, Yingjie Si, +6

Diabetes