Vance L. Mack

Structure/function of the inhibition of human 3β-hydroxysteroid dehydrogenase type 1 and type 2 by trilostane

James L. Thomas, Vance L. Mack, Jason A. Glow et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2008 · 38 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +5

Structure/function of human type 1 3β-hydroxysteroid dehydrogenase: An intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for substrate and coenzyme utilization

James L. Thomas, Robert Huether, Vance L. Mack et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2007 · 21 citations · Full text

Aldehyde Dehydrogenase, Biochemistry, Natural Sciences +6

Structural basis for the selective inhibition of human 3β-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells

James L. Thomas, Kevin M. Bucholtz, Jingping Sun et al. · Molecular and Cellular Endocrinology · 2008 · 14 citations · Full text

Selective Inhibition, Breast Oncology, Biochemistry +8

The functions of key residues in the inhibitor, substrate and cofactor sites of human 3β-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis

James L. Thomas, Vance L. Mack, Jingping Sun et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2010 · 11 citations

Molecular Pharmacology, Key Residues, Biochemistry +5

Regulation of Human 3β-Hydroxysteroid Dehydrogenase Type 2 by Adrenal Corticosteroids and Product-Feedback by Androstenedione in Human Adrenarche

James L. Thomas, Maheshinie Rajapaksha, Vance L. Mack et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 11 citations · Full text