Compromised CD4⁺ CD25^high regulatory T‐cell function in patients with relapsing‐remitting multiple sclerosis is correlated with a reduced frequency of FOXP3‐positive cells and reduced FOXP3 expression at the single‐cell level

Koen Venken, Niels Hellings, Mariëlle Thewissen, +6

Immunology

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Koen Venken, Peggy Jacques, Céline Mortier, +25

Nature Communications

Natural Naive CD4+CD25+CD127low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

Koen Venken, Niels Hellings, Tom Broekmans, +3

The Journal of Immunology

Natural killer T cells in adipose tissue prevent insulin resistance

Henk S. Schipper, Maryam Rakhshandehroo, Stan F.J. van de Graaf, +14

Journal of Clinical Investigation

Metabolic DisorderT-regulatory CellImmunologyInkt CellsImmunotherapy +15

Secondary progressive in contrast to relapsing‐remitting multiple sclerosis patients show a normal CD4⁺CD25⁺ regulatory T‐cell function and FOXP3 expression

Koen Venken, Niels Hellings, Karen Hensen, +6

Journal of Neuroscience Research

Analyses of immunosenescent markers in patients with autoimmune disease

Mariëlle Thewissen, Veerle Somers, Koen Venken, +5

Clinical Immunology

Autoimmune DiseaseAutoantibody ProductionImmunologyAutoimmunityAutoantibodies +3

A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses

Koen Venken, Mariëlle Thewissen, Niels Hellings, +4

Journal of Immunological Methods

InflammationAutoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunology +9

Galactose‐modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

Sandrine Aspeslagh, Yali Li, Esther Dawen Yu, +13

The EMBO Journal

The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD

Elise G De Smet, Hannelore P. Van Eeckhoutte, Francisco Avila Cobos, +9

Mucosal Immunology

InflammationTobacco ControlInflammatory Lung DiseaseAllergyLung Inflammation +7

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70

Meng Zhao, Mattias N. D. Svensson, Koen Venken, +8

Nature Communications