Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes

Jocelyn O. Eidahl, Brandon L. Crowe, Justin A. North, +10

Nucleic Acids Research

Hydrophobic CavityLedgf/p75 InteractionsProtein AssemblyMolecular BiologyProtein Folding +16

BET proteins promote efficient murine leukemia virus integration at transcription start sites

Amit Sharma, Ross C. Larue, Matthew Plumb, +12

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyMolecular BiologyImmunodominanceBet Proteins +15

LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes

Parmit K. Singh, Matthew Plumb, Andrea L. Ferris, +9

Genes & Development

Spliced GenesViral ReplicationMolecular BiologyHiv-1 Integration SitesSplicing Variant +15

Serial Testing for SARS-CoV-2 and Virus Whole Genome Sequencing Inform Infection Risk at Two Skilled Nursing Facilities with COVID-19 Outbreaks — Minnesota, April–June 2020

Joanne Taylor, Rosalind J. Carter, Nicholas Lehnertz, +22

MMWR Morbidity and Mortality Weekly Report

Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction

Sriram Aiyer, G.V.T. Swapna, Nirav Malani, +11

Nucleic Acids Research

Murine Leukemia VirusViral ReplicationSystems BiologyMolecular VirologyNatural Sciences +12

Development of an amplicon-based sequencing approach in response to the global emergence of mpox

Nicholas F. G. Chen, Chrispin Chaguza, Luc Gagne, +67

PLoS Biology

EngineeringGlobal EmergenceViral DiagnosticsGeneticsMolecular Biology +23

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes

Ross C. Larue, Matthew Plumb, Brandon L. Crowe, +9

Nucleic Acids Research

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

Lei Feng, Venkatasubramanian Dharmarajan, Erik Serrao, +11

ACS Chemical Biology

Competitive InterplayHiv-1 IntegraseEngineeringHiv-1 IntegrationMedicine +13

COVID-19 Outbreak Associated with a 10-Day Motorcycle Rally in a Neighboring State — Minnesota, August–September 2020

Melanie J. Firestone, Haley Wienkes, Jacob Garfin, +15

MMWR Morbidity and Mortality Weekly Report

Genomic deletions and rearrangements in monkeypox virus from the 2022 outbreak, USA

Crystal M. Gigante, Matthew Plumb, Ali Ruprecht, +38

Monkeypox VirusGenomic DeletionsGeneticsViral Polymerase MechanismGenomics +16