Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein

Takuma Hashimoto, Daiki D. Horikawa, Yuki Saito, +25

Nature Communications

gVolante for standardizing completeness assessment of genome and transcriptome assemblies

Osamu Nishimura, Yuichiro Hara, Shigehiro Kuraku

Bioinformatics

Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease

Akira Sobue, Okiru Komine, Yuichiro Hara, +10

Acta Neuropathologica Communications

Shark genomes provide insights into elasmobranch evolution and the origin of vertebrates

Yuichiro Hara, Kazuaki Yamaguchi, Koh Onimaru, +21

Nature Ecology & Evolution

Large GenomesGeneticsElasmobranch EvolutionGenomicsPhylogenetics +17

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

Yuka Nakazawa, Yuichiro Hara, Yasuyoshi Oka, +23

Cell

ChromatinTranscriptional RegulationGenome InstabilityMedicineCell Biology +1

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Hiroyuki Konishi, Takayuki Okamoto, Yuichiro Hara, +17

The EMBO Journal

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation

Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, +20

Nature Cell Biology

ChromatinGenome InstabilityNatural SciencesGeneticsGenomic Mechanism +6

Optimizing and benchmarking de novo transcriptome sequencing: from library preparation to assembly evaluation

Yuichiro Hara, Kaori Tatsumi, Michio Yoshida, +3

BMC Genomics

Digenic mutations in <i>ALDH2</i> and <i>ADH5</i> impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome

Yasuyoshi Oka, Motoharu Hamada, Yuka Nakazawa, +38

Science Advances

Diversification of non-visual photopigment parapinopsin in spectral sensitivity for diverse pineal functions

Mitsumasa Koyanagi, Seiji Wada, Emi Kawano‐Yamashita, +8

BMC Biology