Jean‐Luc Décout

Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-(α]-thymidylate covalently linked to an azidoproflavine derivative

Trung Le Doan, Danièle Praseuth, Nourcddine Habhoub et al. · Nucleic Acids Research · 1987 · 489 citations · Full text

Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

Marie‐Paule Mingeot‐Leclercq, Jean‐Luc Décout · MedChemComm · 2016 · 146 citations · Full text

Membrane Anionic Lipids, Antimicrobial Chemotherapy, Antibiotic Resistance +20

The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?

Myriam Ouberaï, Farid El Garch, Antoine Bussière et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2011 · 85 citations

Membrane Formation, Antimicrobial Susceptibility, Antibiotics +8

Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics

Micheline El Khoury, Jitendriya Swain, Guillaume Sautrey et al. · Scientific Reports · 2017 · 78 citations · Full text

Proteinlipid Interaction, Antimicrobial Chemotherapy, Analytical Ultracentrifugation +21

New 7-Methylguanine Derivatives Targeting the Influenza Polymerase PB2 Cap-Binding Domain

Stéphane Pautus, Peter Sehr, Joe Lewis et al. · Journal of Medicinal Chemistry · 2013 · 72 citations

Viral Rna, Drug Target, Antiviral Compound +11