Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema

Hironaka Igarashi, Vincent J. Huber, Mika Tsujita, +1

Neurological Sciences

Cerebrovascular DiseasePharmacotherapyCerebral Vascular RegulationNeurovascular DiseaseMolecular Pharmacology +20

Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke

Masato Kanazawa, Kunio Kawamura, Tetsuya Takahashi, +9

Brain

Water influx into cerebrospinal fluid is primarily controlled by aquaporin-4, not by aquaporin-1

Hironaka Igarashi, Mika Tsujita, Ingrid L. Kwee, +1

Neuroreport

Water FluxOptogeneticsCellular PhysiologyCerebral Vascular RegulationCsf Production +19

Intra-arterial transplantation of bone marrow mononuclear cells immediately after reperfusion decreases brain injury after focal ischemia in rats

Nobuo Kamiya, Masayuki Ueda, Hironaka Igarashi, +4

Life Sciences

TransplantationStem Cell TransplantationHematologyGraft SurvivalVascular Biology +12

<i>In Vivo</i> Visualization of Senile‐Plaque‐Like Pathology in Alzheimer's Disease Patients by MR Microscopy on a 7T System

Tsutomu Nakada, H Matsuzawa, Hironaka Igarashi, +2

Journal of Neuroimaging

Inhibition of VEGF signaling pathway attenuates hemorrhage after tPA treatment

Masato Kanazawa, Hironaka Igarashi, Kunio Kawamura, +6

Journal of Cerebral Blood Flow & Metabolism

ImmunologyPathologyBiomedical EngineeringCerebral Vascular RegulationInflammation +23

Inhibition of aquaporin-4 significantly increases regional cerebral blood flow

Hironaka Igarashi, Mika Tsujita, Yuji Suzuki, +2

Neuroreport

PharmacotherapyExperimental PharmacologySocial SciencesCerebral Vascular RegulationMolecular Pharmacology +20

Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood–brain barrier

Vincent J. Huber, Hironaka Igarashi, Satoshi Ueki, +2

Neuroreport

Synaptic SignalingCerebral Vascular RegulationEpendymaCerebrospinal FluidNeurology +20

Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy

Manabu Natsumeda, Hironaka Igarashi, Toshiharu Nomura, +9

Acta Neuropathologica Communications

Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System

Kenshi Terajima, Hironaka Igarashi, Masaki Hirose, +3

European Neurology

White MatterBrain LesionSerial AssessmentsMagnetic Resonance ImagingBrain Injury +17