Massimo Tatti

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

Isabella Parolini, Cristina Federici, Carla Raggi et al. · Journal of Biological Chemistry · 2009 · 1.5K citations · Full text

Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting

Anna Maria Vaccaro, Marialetizia Motta, Massimo Tatti et al. · Human Molecular Genetics · 2010 · 105 citations

Genetics, Saposin C Mutations, Glycobiology +20

pH-dependent Conformational Properties of Saposins and Their Interactions with Phospholipid Membranes

Anna Maria Vaccaro, Fiorella Ciaffoni, Massimo Tatti et al. · Journal of Biological Chemistry · 1995 · 96 citations · Full text

Structural Analysis of Saposin C and B

Anna Maria Vaccaro, Rosa Salvioli, Alessandra Barca et al. · Journal of Biological Chemistry · 1995 · 82 citations · Full text

Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts

Massimo Tatti, Marialetizia Motta, Sabrina Di Bartolomeo et al. · Human Molecular Genetics · 2012 · 78 citations · Full text

Mitophagy, Immunology, Cell Death +23