<i>N</i>-(3-Fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as Selective Dopamine D3 Receptor Ligands: Critical Role of the Carboxamide Linker for D3 Receptor Selectivity

Ashwini K. Banala, Benjamin Levy, Sameer S. Khatri, +7

Journal of Medicinal Chemistry

Amide LinkerD3r SelectivityMolecular PharmacologyMedicinal ChemistryD3 Receptor Selectivity +16

The Tetrahydroisoquinoline Derivative SB269,652 Is an Allosteric Antagonist at Dopamine D3 and D2 Receptors

Elena Silvano, Mark J. Millan, Clotilde Mannoury la Cour, +9

Molecular Pharmacology

Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes

Robert R. Luedtke, Suzy A. Griffin, Susan S Conroy, +3

Journal of Neuroimmunology

Rat D1aFunctional SelectivityNeuroanatomyMedicineImmunology +7

Evaluation of D2 and D3 dopamine receptor selective compounds on l-dopa-dependent abnormal involuntary movements in rats

Rakesh Kumar, Lindsay R. Riddle, Suzy A. Griffin, +5

Neuropharmacology

NeurophysiologyMedicineFunctional SelectivityPhysiologyReceptor Selective Compounds +8

Evaluation of the D3 dopamine receptor selective antagonist PG01037 on l-dopa-dependent abnormal involuntary movements in rats

Rakesh Kumar, Lindsay R. Riddle, Suzy A. Griffin, +3

Neuropharmacology

Functional SelectivityPhysiologyNeuropharmacologyMotor ControlNeuroscience +5

Highly Selective Dopamine D₃ Receptor Antagonists with Arylated Diazaspiro Alkane Cores

Sean W. Reilly, Suzy A. Griffin, Michelle Taylor, +6

Journal of Medicinal Chemistry

Comparison of the Binding and Functional Properties of Two Structurally Different D2 Dopamine Receptor Subtype Selective Compounds

Robert R. Luedtke, Yogesh Mishra, Qi Wang, +8

ACS Chemical Neuroscience

Functional PropertiesPharmacotherapyChemistryPharmaceutical ChemistryMedicinal Chemistry +14

Analogues of Arylamide Phenylpiperazine Ligands To Investigate the Factors Influencing D3 Dopamine Receptor Bitropic Binding and Receptor Subtype Selectivity

Hamed S. Hayatshahi, Kuiying Xu, Suzy A. Griffin, +4

ACS Chemical Neuroscience

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands

Peng-Jen Chen, Michelle Taylor, Suzy A. Griffin, +9

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryFunctional SelectivityNatural SciencesMedicine +5

Typical antipsychotics exhibit inverse agonist activity at rat dopamine D1-like receptors expressed in Sf9 cells

Michael Wade Martin, Allelia W. Scott, Douglas E. Johnston, +2

European Journal of Pharmacology

Inverse Agonist ActivityPsychiatryFunctional SelectivityMedicinePsychotropic Medication +10