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Publications
7
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Active since
2003
Affiliations
Harvard University(Current)
Pfizer (United States)
Michelle Pacholec is an author at Harvard University specializing in biochemistry, life sciences, and enzymology.
Publications per year
2003–2010
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
Michelle Pacholec, John E. Bleasdale, Boris A. Chrunyk et al. · Journal of Biological Chemistry · 2010 · 896 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +13
CouO and NovO: C-Methyltransferases for Tailoring the Aminocoumarin Scaffold in Coumermycin and Novobiocin Antibiotic Biosynthesis
Michelle Pacholec, Junhua Tao, Christopher T. Walsh · Biochemistry · 2005 · 63 citations
Life Sciences, Biochemistry, Microbiology +8
Characterization of the Aminocoumarin Ligase SimL from the Simocyclinone Pathway and Tandem Incubation with NovM,P,N from the Novobiocin Pathway
Michelle Pacholec, Caren L. Freel Meyers, Markus Oberthür et al. · Biochemistry · 2005 · 28 citations
Life Sciences, Biochemistry, Medicinal Chemistry +9
Synthesis of Proposed Oxidation−Cyclization−Methylation Intermediates of the Coumarin Antibiotic Biosynthetic Pathway
Junhua Tao, Shanghui Hu, Michelle Pacholec et al. · Organic Letters · 2003 · 25 citations
Pharmacy, Medicinal Chemistry, Bioorganic Chemistry +12
Formation of an aminoacyl-S-enzyme intermediate is a key step in the biosynthesis of chloramphenicol
Michelle Pacholec, Jason K. Sello, Christopher T. Walsh et al. · Organic & Biomolecular Chemistry · 2007 · 24 citations
Life Sciences, Biochemistry, Microbiology +3
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