Alan Sielaff

Hx, a Novel Fluorescent, Minor Groove and Sequence Specific Recognition Element: Design, Synthesis, and DNA Binding Properties of <i>p</i>-Anisylbenzimidazole-imidazole/pyrrole-Containing Polyamides

Sameer Chavda, Yang Liu, Balaji Babu et al. · Biochemistry · 2011 · 27 citations

Natural Sciences, Chemistry, Molecular Biology +15

Binding of f-PIP, a pyrrole- and imidazole-containing triamide, to the inverted CCAAT box-2 of the topoisomerase IIα promoter and modulation of gene expression in cells

N. Minh Le, Alan Sielaff, Amanda J. Cooper et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 17 citations

Life Sciences, Genetics, Molecular Biology +11

Sequence specific and high affinity recognition of 5′-ACGCGT-3′ by rationally designed pyrrole-imidazole H-pin polyamides: Thermodynamic and structural studies

Hilary Mackay, Toni Brown, Peter B. Uthe et al. · Bioorganic & Medicinal Chemistry · 2008 · 16 citations

Natural Sciences, Biochemistry, Chemistry +16

Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm

Toni Brown, Hilary Mackay, Mark Turlington et al. · Bioorganic & Medicinal Chemistry · 2008 · 16 citations

Life Sciences, Chemistry, Molecular Biology +4