Grégory Segala

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Maud Voisin, Philippe de Médina, Arnaud Mallinger et al. · Proceedings of the National Academy of Sciences · 2017 · 119 citations · Full text

Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands

Philippe de Médina, Michaël R. Paillasse, Grégory Segala et al. · Proceedings of the National Academy of Sciences · 2010 · 118 citations · Full text

Pharmacological Characterization, Breast Oncology, Tamoxifen Binding +20

Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

Philippe de Médina, Michaël R. Paillasse, Grégory Segala et al. · Nature Communications · 2013 · 115 citations · Full text

Dendrogenin A drives LXR to trigger lethal autophagy in cancers

Grégory Segala, Marion David, Philippe de Médina et al. · Nature Communications · 2017 · 101 citations · Full text

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis

Abhinav Joshi, Li Dai, Yanxin Liu et al. · BMC Biology · 2020 · 86 citations · Full text