23:T4fc,Cholera, an acute gastro-intestinal infection and a waterborne disease continues to emerge in developing countries and remains an important global health challenge. In this paper, we formulate a mathematical model that captures some essential dynamics of cholera transmission with public health educational campaigns, vaccination, sanitation and treatment as control strategies in limiting the disease. The reproduction numbers with single and combined controls are computed and compared with each other to assess the possible community benefits. Numerical simulation shows that in a unique control strategy, treatment yields the best results followed by education campaign, then sanitation and vaccination being the last. Furthermore, we noted that the control of cholera is very much better when we incorporated more than one strategy, in two controls the results were better than one strategy, and in three control strategies the results were far better than in two control strategies. Further simulations with all four interventions showed the best results among all combinations attained before. We performed sensitivity analysis on the key parameters that drive the disease dynamics in order to determine their relative importance to disease transmission and prevalence.24:T52b,In this paper we formulate a deterministic mathematical model for the transmission dynamics of rabies in human and animal within and around Addis Ababa, Ethiopia. Our model involves vaccination program for dog population. The basic reproduction number and effective reproduction numbers are computed and the results are entirely depending on the parameters of dog population, which shows the responsibility of dog population for human and livestock infection. For a specified set of values of parameters as deduced from the data provided by Ethiopian Public Health Institute of Addis Ababa, the basic reproduction number R₀ and the effective reproduction number R_e works out to be 2 and 1.6 respectively, which indicates the disease will be endemic. The numerical simulation of reproduction ratio shows that the combination of vaccination, culling of stray dogs and controlling annual crop of new born puppies are the best method to control rabies transmission within and around Adds Ababa. The disease - free equilibrium ε₀ is computed. When the effective reproduction number R_e<1 it is proved to be globally asymptotically stable in the feasible region Φ. When R_e>1 there exists one endemic equilibrium point which is locally asymptotically stable.25:T57d,

#	Concept	H-Index	Publications	Citations
1	Engineering	16	30	672
2	Medicine	6	6	213
3	Management	3	3	218
4	Education	1	1	12
5	Natural Sciences	1	1	22

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