Concentration of serum interleukin-27 increase in patients with lymph node metastatic gastroesophageal cancer.

Abstract

Our results demonstrated that a high serum IL-27 level is associated with cancer presence and lymph node metastases in GEC. Significantly higher levels of IL-27 in patients with esophageal squamous cell carcinoma after tumor resection may imply that host immune cells are one of the important sources of circulating IL-27.