Concepedia

miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2.

Junjie Zhang, Chenyu Wang, Hua Long, Kunhou Yao, Jiangtao Chen, Junhong Hu

PubMed · 2015 · 46 citations · 17 references

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Abstract

Our observations suggested that miR-107 could promote HCC cells proliferation via targeting Axin2 and might represent a potential therapeutic target for HCC.

References

17

Global cancer statistics

Ahmedin Jemal, Freddie Bray · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

Eek‐hoon Jho, Tong Zhang, Claire Domon–Dell et al. · Molecular and Cellular Biology · 2002 · 1.7K citations · Full text

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

Munekazu Yamakuchi, Craig Lotterman, Clare Bao et al. · Proceedings of the National Academy of Sciences · 2010 · 429 citations · Full text

miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans

Pai‐Sheng Chen, Jen-Liang Su, Shih-Ting Cha et al. · Journal of Clinical Investigation · 2011 · 151 citations · Full text

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Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: Clinical Characteristics, Prognosis, and Patient Survival Analysis

Daichi Takizawa, Satoru Kakizaki, Naondo Sohara et al. · Digestive Diseases and Sciences · 2007 · 144 citations

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