Concepedia

Pterostilbene attenuates inflammation in rat heart subjected to ischemia-reperfusion: role of TLR4/NF-κB signaling pathway.

Chen Wang, Hourong Sun, Yi Song, Zengshan Ma, Gong Zhang, Xinghua Gu, Lei Zhao

PubMed · 2015 · 29 citations · 27 references

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Abstract

These data provide evidence that pterostilbene inhibits TLR4/NF-κB signaling and apoptosis in the rat heart subjected to MI/R, which is associated with NO production.

References

27

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology · 1999 · 3.4K citations · Full text

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

Yumiko Imai, Keiji Kuba, G. Gregory Neely et al. · Cell · 2008 · 1.3K citations · Full text

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Fibrinogen Stimulates Macrophage Chemokine Secretion Through Toll-Like Receptor 4

Stephen T. Smiley, Jennifer King, Wayne W. Hancock · The Journal of Immunology · 2001 · 951 citations · Full text

HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2

Man Yu, Haichao Wang, Aihao Ding et al. · Shock · 2006 · 816 citations

Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium

Stefan Frantz, Lester Kobzik, Young‐Dae Kim et al. · Journal of Clinical Investigation · 1999 · 646 citations · Full text