T and B lymphocytes in three population groups

Abstract

The lymphocytes of 166 normal subjects from three population groups were studied by a method in which T and B cells were enumerated in a single preparation, using sheep cell rosette formation together with immunofluorescence for surface immunoglobulins. Ninety-four per cent of peripheral lymphocytes could be classified into one or the other group, with no overlapping except in five subjects who had some cells carrying both markers. Total absolute lymphocyte, T- and B-cell counts were highest in Indians, with significant differences against both the other groups, and lowest in Europeans, with African Negroes showing intermediate values.