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Ehrlichiosis presenting with toxic shock-like syndrome and secondary hemophagocytic lymphohistiocytosis.
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2013
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Human Monocytotropic EhrlichiosRheumatologyVasculitisAutoimmune DiseasePathogenesisHematologyImmunologyPathologySepsisEhrlichia SepsisAutoimmunityMedicineRheumatoid ArthritisTick-borne DiseaseToxic Shock-like Syndrome
Human monocytotropic ehrlichios is a tick borne illness caused by Ehrlichia chaffeensis. Ehrlichiosis presenting with septic shock and severe azotemia is rare, and may be seen in immunocompromised individuals. We present a case of ehrlichia induced toxic shock like syndrome in a patient with rheumatoid arthritis on disease modifying agents. He also had oliguric renal failure requiring dialysis on presentation and later found to have Hemophagocytic Lymphohistiocytosis secondary to severe ehrlichia sepsis.