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CD4+CD25+Foxp3+ Treg and TGF-beta play important roles in pathogenesis of Uygur cervical carcinoma.

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References

2012

Year

Chen Zf, Qiao Shi Xu, Junqiang Ding, Yunjian Zhang, Rui‐Hong Du, Yi Ding
PubMed

Abstract

Finally, the authors would like to highlight that CD4+CD25+ Treg, especially the CD4+CD25+Foxp3+ Treg and TGF-beta play important roles in Uygur cervical carcinoma, and may have a correlation with survival. Therefore, the inhibitory function of TGF-beta depletion of Treg cells in combination with other anti-tumor therapies could optimize eradication of malignancies.