Loss of Aggression, After Transfer onto a C57BL/6J Background, in Mice Carrying a Targeted Disruption of the Neuronal Nitric Oxide Synthase Gene

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

Alcino J. Silva, Charles F. Stevens, Susumu Tonegawa et al. · Science · 1992 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +17

Targeted disruption of the neuronal nitric oxide synthase gene

Paul L. Huang, Ted M. Dawson, David S. Bredt et al. · Cell · 1993 · 1.3K citations

Life Sciences, Genetics, Neuroscience +11

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

Robert Gerlai · Trends in Neurosciences · 1996 · 885 citations

Life Sciences, Genetics, Molecular Biology +14

Serotonin receptor 1A knockout: An animal model of anxiety-related disorder

Sylvie Ramboz, Ronald S. Oosting, Djamel Aït Amara et al. · Proceedings of the National Academy of Sciences · 1998 · 810 citations

Life Sciences, Neuroscience, Psychology +17

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

Elizabeth M. Simpson, C. Linder, Evelyn E. Sargent et al. · Nature Genetics · 1997 · 700 citations

Life Sciences, Genetics, Molecular Genetics +6