PubMed · 1978 · 23 citations · 5 references
MedicineOncologyPharmacologyClinical Radiation OncologyMedical OncologyOncology PharmacotherapyChemotherapy Drug AdministrationDose Adjustment In OncologyRadiation TherapyRadiobiological ConsiderationsDosage RegulationFractionated TreatmentTherapeutic Dosimetry
A total of 62 patients with advanced tumours have now been treated by a fractionated course of radiotherapy, with misonidazole. The prime purpose of the administration of the drug to these patients was to determine safe dosage and suitable regimes for use in clinical radiotherapy. The reaction of normal tissues did not seem enhanced but there was an impression of increased tumour response.
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Clinical testing of the radiosensitizer Ro 07-0582: Experience with multiple doses
Stanley Dische, Megan I. Saunders, M E Lee et al. · British Journal of Cancer · 1977 · 259 citations
Clinical testing of the radiosensitiser Ro-07-0582 III. Response of tumours
R. H. Thomlinson, Stanley Dische, Alan Gray et al. · Clinical Radiology · 1976 · 119 citations