PubMed · 1978 · 164 citations · 9 references
Life SciencesGeneticsMolecular GeneticsHuman GeneticsImmunogeneticsMedical GeneticsAntibody StructureEvolution Of Immune GenesImmunogenomicsImmunoglobulin DiversityImmunoglobulin Gene RearrangementSerum Specific Immunoglobulin E TestingGermline Antibody Gene VariationGermline Immunoglobulin Gene UsageImmunoglobulin Gene PolymorphismImmunoglobulin Gene SegmentsImmunoglobulin Gene Variation
Path analysis gives evidence of genetic heritability (.425) for serum IgE levels. Complex segregation analysis indicates, in addition to significant polygenic heritability, a major regulatory locus RE, with homozygotes re/re maintaining persistently high levels of IgE. The gene frequency of re is .489, and the displacement is 1.67 standard deviations.
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RAISED LEVELS OF A NEW IMMUNOGLOBULIN CLASS (IgND) IN ASTHMA
S. G. O. Johansson · The Lancet · 1967 · 470 citations
Skewness in Commingled Distributions
C J MacLean, Newton E. Morton, Robert C. Elston et al. · Biometrics · 1976 · 329 citations