Canadian Respiratory Journal · 2013 · 84 citations · 5 references
PharmacyPharmacologyPharmacotherapyClinical PharmacologyHypersensitivityPharmaceutical ToxicologyDermatologic Toxicity ManagementHypersensitivity PneumonitisPulmonary ToxicityPulmonary Toxicity ManagementPulmonary ToxicologyRespiratory ToxicologyAdverse Drug Reaction InterpretationDrug-induced PneumonitisDrug-related PneumonitisMethotrexate ProphylaxisMethotrexate Toxicity PreventionPsoriasis ImmunopathologyPsoriasis TherapyPsoriatic Disease
Methotrexate is a widely used medication with an array of recognized side effects. The present report describes a case of methotrexate-induced pneumonitis in a patient with psoriasis, and demonstrates the hallmark clinical and investigational findings that support this infrequently encountered diagnosis. The ensuing discussion reviews the pathogenesis, management and prevention of this adverse drug reaction.
5
Bronchoalveolar lavage cell profile in methotrexate induced pneumonitis
A. Schnabel, C. Richter, S. Bauerfeind et al. · Thorax · 1997 · 98 citations
Medicine, Immunology, Pathology +16