Uremic bone disease: current knowledge, controversial issues, and new horizons.

Hartmut H. Malluche, M-C Monier-Faugere

PubMed · 1991 · 15 citations · 0 references

Concepts

Abstract

Abnormalities in mineral and bone metabolism occur early in the course of renal failure and uremic bone disease is a major contributing factor to the morbidity of patients with end-stage renal failure. In addition, new therapeutic approaches have generated new outlooks, problems and controversies. This article reviews our current accepted knowledge, the present numerous controversies, unresolved questions, new issues and new horizons.