STUDIES ON THE CORONARY CIRCULATION. VI. LOSS OF MYOCARDIAL CONTRACTILITY AFTER CORONARY ARTERY OCCLUSION

Abstract

Article1 September 1949STUDIES ON THE CORONARY CIRCULATION. VI. LOSS OF MYOCARDIAL CONTRACTILITY AFTER CORONARY ARTERY OCCLUSIONMYRON PRINZMETAL, M.D., LOIS L. SCHWARTZ, M.D., ELIOT CORDAY, M.D., RAMON SPRITZLER, M.D., H. C. BERGMAN, H. E. KRUGERMYRON PRINZMETAL, M.D., LOIS L. SCHWARTZ, M.D., ELIOT CORDAY, M.D., RAMON SPRITZLER, M.D., H. C. BERGMAN, H. E. KRUGERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-3-429 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONIt is well known clinically and experimentally that an ischemic portion of myocardium may bulge or "balloon" out during systole.1This remarkable phenomenon, which is of diagnostic and physiologic importance, has been very difficult to study in the past. Clinically, it has been observed on patients under the fluoroscope and may be graphically recorded by the electrokymogram and roentgenkymogram.2-8The information that can be obtained by such clinical procedures is relatively limited. At best, these clinical methods can tell us only whether bulging in systole is or is not present. It is highly probable that slight degrees of bulging...Bibliography1. TENANTWIGGERS RCJ: The effect of coronary occlusion on myocardial contraction, Am. Jr. Physiol., 1935, cxii, 351. CrossrefGoogle Scholar2. HIRSCHGUBNER ISR: Application of roentgenkymography to study of normal and abnormal physiology, Am. Heart Jr., 1936, xii, 413. CrossrefGoogle Scholar3. GUBNERCRAWFORD RIH: Roentgenkymographic studies of myocardial infarction, Am. Heart Jr., 1939, xviii, 8. CrossrefGoogle Scholar4. SUSSMANDACKMASTER MLSAM: The roentgenkymogram in myocardial infarction. I. The abnormalities in left ventricular contraction, Am. Heart Jr., 1940, xix, 453. 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HARRISMATLOCK ASWP: The effect of anoxemic anoxia upon conduction and excitability of mammalian cardiac muscle in situ, Proc. Fed. Soc. Exper. Biol., 1947, vi, 123. Google Scholar18. DRURY AN: Further observations upon intra-auricular block produced by pressure or cooling, Heart, 1925, xii, 143. Google Scholar19. SAMPSON JJ: Personal communication. Google Scholar20. THOMASGARLAND SFLH: Roentgen cardiac diagnosis, Calif. Med., 1948, lxviii, 126. Google Scholar21. WIGGERS CJ: Physiology in health and disease, 1944, Lea and Febiger, Philadelphia. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California*Presented at the Twenty-Ninth Annual Session of the American College of Physicians, San Francisco, California, April 23, 1948.From the Institute for Medical Research, Cedars of Lebanon Hospital, Los Angeles, California.Aided by grants from the Blanche May and Beaumont Trust Funds. 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