OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · 1971 · 12 citations · 0 references
Germ-line BRCA1 mutations can be present in young women with breast cancer who do not belong to families with multiple affected members. The specific BRCA1 mutation known as 185delAG is strongly associated with the onset of breast cancer in Jewish women before the age of 40.