Characterization of a Hot-Melt Fluid Bed Coating Process for Fine Granules

Empirical Model Building and Response Surfaces

Anne E. Freeny, George E. P. Box, Norman R. Draper · Technometrics · 1988 · 5.1K citations

Public Health, Design, Design Optimization +12

On the Experimental Attainment of Optimum Conditions

George E. P. Box, Kerry Wilson · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1951 · 4.4K citations

Public Health, Mathematics, Experimental Design +4

Response Surface Methodology

Raymond H. Myers, Douglas C. Montgomery · IIE Transactions · 1996 · 3.8K citations

Computing, Computational Engineering, Algorithms +13

Mathematical Optimization Techniques in Drug Product Design and Process Analysis

Dale E. Fonner, James R. Buck, Gilbert S. Banker · Journal of Pharmaceutical Sciences · 1970 · 96 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +16

Computer Optimization of Pharmaceutical Formulations I: General procedure

Joseph B. Schwartz, Joel R. Flamholz, Robert Press · Journal of Pharmaceutical Sciences · 1973 · 84 citations

Pharmacy, Pharmaceutics, Dosage Form Design +8