Ophthalmic surgery, lasers & imaging retina · 2004 · 17 citations · 29 references
Health ProfessionsOphthalmologyVeterinary OphthalmologyOcular AnatomyOcular ImagingPediatric OphthalmologyOptical Coherence TomographyRetinal AnatomyRetinal DiseaseRetinal DisordersRetinal ExaminationRetinal ImagingMacular Optical Coherence TomographyMacular Thickness MeasurementOcular Coherence TomographyOptical Coherence Tomography FindingsRetinal Layer ThicknessRetinal Nerve Fiber Layer AnalysisRetinal Nerve Fiber Layer ThinningRetinal Thickness Analysis
BACKGROUND AND OBJECTIVE: To compare retinal thickness and retinal nerve fiber layer (RNFL) thickness values obtained by optical coherence tomography (OCT) in normal dogs and dogs with rod-cone dysplasia type 1 (RCD1). MATERIALS AND METHODS: Eight eyes of 6 normal hound-bred dogs and 12 eyes of 6 dogs with RCD1, 2 to 5 years of age, were examined using the Fast RNFL Thickness, Fast Macular Thickness, and line scan protocols of OCT. RESULTS: Retinal thickness was significantly higher in the tapetal fundus than in the non-tapetal fundus, in both normal (P = .0036) and RCD1 (P < .0001) dogs. Superotemporal, superonasal, and inferior retinal thickness values were significantly higher in normal dogs (P < .0001). Area centralis thickness was 183.5 +/- 10.66 microm in normal dogs and 136.16 +/- 13.12 microm in RCD1 dogs (P < .0001). There was no difference in RNFL thickness between normal and RCD1 dogs (P > .05). CONCLUSION: OCT scanning in dogs is considered to be a useful method of evaluation in future retinal studies in this animal model.
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Preservation of the Inner Retina in Retinitis Pigmentosa
Arturo Santos · Archives of Ophthalmology · 1997 · 643 citations