PubMed · 1994 · 10 citations · 0 references
MedicineDermatologyPathologyDermatopathologyMolecular PathologyPhotodermatologyImmunopathology Of SkinInflammatory DermatosesInflammatory Skin DiseasesInflammatory Skin DisordersPsoralen Plus Ultraviolet A TherapyAntinuclear Antibody PositivityCreatine Kinase-mbCutaneous ImmunologyDermatomyositis Skin DiseaseLaboratory AbnormalitiesProximal Muscle Weakness EvaluationPsoriatic DiseaseSerum Creatine Kinase Assessment
Dermatomyositis (DM) developed in a 35-year-old woman after 2 months of psoralen ultraviolet-A (PUVA) therapy for presumed psoriasis. Her disease was characterized by symmetrical proximal muscle weakness and cutaneous lesions compatible with DM. In addition, laboratory abnormalities included a positive antinuclear antibody, and elevated levels of creatine kinase and aldolase. This is the first report of DM developing during PUVA therapy.