The internal horizontal cell of the frog. Analysis of receptor input.

Abstract

The inner horizontal cell (IHC) of the retina of Rana pipiens was studied by light and electron microscopy of Golgi stained or horseradish peroxidase injected cells. Responses of IHCs were recorded with intracellular electrodes. Both axon and dendritic terminals of the IHC make synaptic contact with all classes of receptor. The terminals occur as lateral or medial processes at synaptic ribbons. Reciprocal invaginations of receptor into horizontal cell process are common. Different classes of receptor are contacted in about the proportions with which they occur in the retina. No tendency for contacts of one type of receptor to occur on a particular part of the cell was found. The IHC generates L-type S-potentials. Both rod and cone input is evident in the waveform of the response, its spectral sensitivity, and the effect on it of adaptation.