PubMed · 2000 · 68 citations · 17 references
Veterinary MedicineInfectious DiseasesPharmacotherapyClinical ImmunologyDiagnostic ParasitologyInfectious Disease PharmacotherapyIncidence StudiesSexually Transmitted InfectionsContagious Disease SpreadEfficacy ReassessmentFomite Transmission ControlPathogenesis Of ScabiesScabies EpidemiologyScabies TransmissionScabies TreatmentSingle-dose Therapy
Scabies is a highly contagious infestation that causes considerable discomfort. Newer information concerning therapeutics and epidemiologic dogma needs assessment. An epidemiologic evaluation of available world data is analyzed, as well as an assessment of therapeutic alternatives. Using epidemiologic techniques, the following points are proven: scabies is not primarily a sexually transmitted disease; 30-year cycles of scabies do not exist; scabies spreads in households and neighborhoods in which there is a high frequency of intimate personal contact or sharing of inanimate objects; and fomite transmission is a major factor in household and nosocomial passage of scabies. Epidemiologic evaluation proves the necessity of fomite precautions and of treatment of asymptomatic family members and physical contacts of all cases of scabies. Single oral-dose therapy of ivermectin (Stromectol) appears to be the treatment panacea for this infestation.
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The Treatment of Scabies with Ivermectin
Terri L. Meinking, David Taplin, Rube J. Pardo et al. · New England Journal of Medicine · 1995 · 302 citations
Comparison of ivermectin and benzyl benzoate for treatment of scabies.
Philippe Glaziou, J L Cartel, P Alzieu et al. · PubMed · 1993 · 129 citations