PubMed · 1980 · 21 citations · 0 references
MedicinePathobiologyPathologyHistologyHistopathologyNeuropathologyCollagen DepositionConnective TissueConnective Tissue DiseasesNervous System PathologyNervous TissuePeripheral Nerve BiopsyCollagen BiologyHistopathology Of Peripheral NerveLeprosy LesionsNervous Tissue HistologyPeripheral Nerve HistologyPolarization
The collagen of nerve biopsies from ten leprosy patients was studied by the Picrosirius-polarization method and electron microscopy. It was observed that leprosy promotes a marked increase in nerve collagen content. Despite the changes induced by this disease, the localization of collagen types I and III in the endo-, peri-, and epineurium remains the same as in normal nerves.