The formation of citric and α-ketoglutaric acids in the mammalian body

Abstract

FROM experiments reported in a previous paper [Krebs & Johnson, 1937] we concluded that carbohydrate is oxidized in animal tissues through the following series of reactions: Oxaloacetic acid + carbohydrate derivative / \ (pyruvic acid?) l-Malic acid Citric acid t Fumaric acid a-Ketoglutaric acid Succinic acid