Effect of sulphydryl-combining compounds on the activity of the succinic oxidase system

Abstract

1.The presence of an active mono-amine oxidase in uterus has been confirmed.Evidence is presented indicating that in the human uterus, and possibly also in the rat uterus, it is mainly localized in the endometrium.2. Human, rat, rabbit and guinea-pig placentas have also been found to be potent sources of the enzyme.3. The level of enzymic activity in rat placenta (expressed per g. of tissue) appears to increase as the placenta matures in utero.4. The activity of the placental enzyme, like that of the enzyme in liver, is proportional to the oxygen tension of the medium in which it acts, a fall of oxygen tension causing a marked fall in rate of enzyme action.