Clinical Pharmacology & Therapeutics · 1970 · 41 citations · 0 references
Life SciencesImmunologyMicrobiologyAntimicrobial PharmacotherapyImmunology Of Infectious DiseasesInnate ImmunityAntibacterial AgentsAntimicrobial TherapyBacterial InfectionsPhagocyte BiologyAntimicrobial KillingInterference With PhagocytosisPhagocyte ActivationPhagocyte Antimicrobial ActivityPhagocyte DysfunctionPhagocyte Killing DefectsPhagocytic ActivityPhagocytosis Of Bacteria
Tetracycline, polymyxin B, and rifampin (an investigational, semisynthetic antibiotic) did not affect engulfment or intraleukocyte killing of bacteria by leukocytes derived from the peripheral blood of normal volunteers. The augury of unimpaired phagocytic function in the infected human being under treatment with either of these agents has clinical support.